Diisopropylethylamine → Ethyl 2-{3-[(tert-butoxycarbonyl)amino]azetidin-1-yl)-4-n-butyl-1,3-thiazole-5-carboxylate

HRID 149794

반응식

[Br:13][c:14]1[s:15][c:16]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[c:17]([CH2:19][CH2:20][CH2:21][CH3:22])[n:18]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][NH:11][CH2:12]1.[CH:28]([N:29]([CH:30]([CH3:31])[CH3:32])[CH2:33][CH3:34])([CH3:35])[CH3:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]1[CH2:10][N:11]([c:14]2[s:15][c:16]([C:23](=[O:24])[O:25][CH2:26][CH3:27])[c:17]([CH2:19][CH2:20][CH2:21][CH3:22])[n:18]2)[CH2:12]1

참가 물질

반응물 3

HCID 81531Diisopropylethylamine

HCID 15194053-Aminoazetidine, 3-BOC protected

HCID 67549203Ethyl 2-bromo-4-n-butyl-1,3-thiazole-5-carboxylate

생성물 1

HCID 67548951Ethyl 2-{3-[(tert-butoxycarbonyl)amino]azetidin-1-yl)-4-n-butyl-1,3-thiazole-5-carboxylate

출처 및 근거

ORD 기록: ord-88a9dda1b3684338881f653d6cb07c1e
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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