Hydrochloric Acid → tert-Butyl 4-((4-(2-fluoro-4-(1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamido)phenoxy)-6-methoxyquinolin-7-yloxy)methyl)piperidine-1-carboxylate
반응식
[CH3:28][CH2:29][N:30]=[C:31]=[N:32][CH2:33][CH2:34][CH2:35][N:36]([CH3:37])[CH3:38].[ClH:39].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9](=[O:17])[c:10]([C:14](=[O:15])[OH:16])[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1.[NH2:40][c:41]1[cH:42][c:43]([F:75])[c:44]([O:45][c:46]2[cH:47][cH:48][n:49][c:50]3[cH:51][c:52]([O:58][CH2:59][CH:60]4[CH2:61][CH2:62][N:63]([C:66](=[O:67])[O:68][C:69]([CH3:70])([CH3:71])[CH3:72])[CH2:64][CH2:65]4)[c:53]([O:56][CH3:57])[cH:54][c:55]23)[cH:73][cH:74]1.[O:76]=[CH:77][N:78]([CH3:79])[CH3:80].[OH:18][n:19]1[c:20]2[c:21]([cH:22][cH:23][cH:24][cH:25]2)[n:26][n:27]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9](=[O:17])[c:10]([C:14](=[O:16])[NH:40][c:41]3[cH:42][c:43]([F:75])[c:44]([O:45][c:46]4[cH:47][cH:48][n:49][c:50]5[cH:51][c:52]([O:58][CH2:59][CH:60]6[CH2:61][CH2:62][N:63]([C:66](=[O:67])[O:68][C:69]([CH3:70])([CH3:71])[CH3:72])[CH2:64][CH2:65]6)[c:53]([O:56][CH3:57])[cH:54][c:55]45)[cH:73][cH:74]3)[cH:11][cH:12][cH:13]2)[cH:6][cH:7]1참가 물질
7
반응물 6
HCID 313Hydrochloric Acid
HCID 6228Dimethylformamide
HCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide
HCID 757711-Hydroxybenzotriazole
HCID 210815271-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid
HCID 59342474tert-Butyl 4-(((4-(4-amino-2-fluorophenoxy)-6-methoxyquinolin-7-yl)oxy)methyl)piperidine-1-carboxylate