Triphenylphosphine → N-Boc-Imino-(triphenyl)phosphorane

HRID 1504266

반응식

HRID 1504266 반응식
[C:1]([N:8]=[N+]=[N-])(=[O:7])[O:2][C:3]([CH3:6])([CH3:5])[CH3:4].[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(OCC)C>[C:24]1([P:17]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[N:8][C:1]([O:2][C:3]([CH3:6])([CH3:5])[CH3:4])=[O:7])[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=1

참가 물질

4

반응물 2

HCID 11776TriphenylphosphineHCID 61256Carbonazidic acid, 1,1-dimethylethyl ester

생성물 1

HCID 2756802N-Boc-Imino-(triphenyl)phosphorane

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

To the solution of t-butyl carbonazidate in diethyl ether, 49.6 g (0.189 mol) of triphenylphosphine was added in small portions under cooling with ice, and the reaction solution was stirred at room temperature for 1 hour, and the precipitated solid was collected by filtration, washed with 200 mL of hexane and dried under reduced pressure to give 67 g of the desired product as white crystals.

후처리

  1. temperatureunder cooling with ice
  2. filtrationthe precipitated solid was collected by filtration
  3. washwashed with 200 mL of hexane
  4. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-441a21346bfd4125b00f912dba81f7fb
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09212348B2

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