Carbon Tetrachloride → Ethyl 2-chloro-2-(o-tolylimino)acetate

HRID 1506628노트

반응식

HRID 1506628 반응식
O=[C:2]([NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])[C:3]([O:5][CH2:6][CH3:7])=[O:4].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(Cl)(Cl)(Cl)[Cl:36]>>[Cl:36][C:2](=[N:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:15])[C:3]([O:5][CH2:6][CH3:7])=[O:4]

참가 물질

4

반응물 3

HCID 5943Carbon TetrachlorideHCID 11776TriphenylphosphineHCID 366755Ethyl [(2-methylphenyl)amino](oxo)acetate

생성물 1

HCID 90280270Ethyl 2-chloro-2-(o-tolylimino)acetate

실험 절차

The suspension of ethyl 2-oxo-2-(o-tolylamino)acetate (2.0 g, 10 mmol) and triphenylphosphine (4.0 g, 15 mmol) in carbon tetrachloride (150 mL) was refluxed overnight. The reaction was cooled down and filtered. The filtrate was collected and concentrated and used it without further purification. MS (m/z) 226 [M+H]+.

후처리

  1. temperaturewas refluxed overnight
  2. temperatureThe reaction was cooled down
  3. filtrationfiltered
  4. customThe filtrate was collected
  5. concentrationconcentrated
  6. customwithout further purification

출처 및 근거

ORD 기록
ord-e2541b6eee964802a631689e192c3bde
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09220710B2

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