Methanol → HCID 117676157, 화합물

HRID 1506881노트

반응식

HRID 1506881 반응식
[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[C:4]([F:11])[C:3]=1[CH:12]([CH3:16])[C:13]([OH:15])=[O:14].[CH3:17]O>Cl>[F:1][C:2]1[CH:7]=[C:6]([N+:8]([O-:10])=[O:9])[CH:5]=[C:4]([F:11])[C:3]=1[CH:12]([CH3:16])[C:13]([O:15][CH3:17])=[O:14]

참가 물질

4

반응물 2

HCID 887MethanolHCID 534295682-(2,6-Difluoro-4-nitrophenyl)propanoic acid

생성물 1

HCID 117676157HCID 117676157, 화합물수율 89%

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

Compound (27b) (3.6 g, 15.6 mmol) was dissolved in a solution of a catalytic amount of concentrated hydrochloric acid (0.14 mL) in methanol (72 mL) and treated in the same manner as in (c) in Production Example 1 to give 3.4 g (89%) of compound (28b) as pale yellow oil.

출처 및 근거

ORD 기록
ord-4f507540534e416d9131d48014a96221
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09221786B2

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