Benzenesulfonyl chloride → Methyl 2-benzenesulphonylamino-5-ethyl-4-methylthiophene-3-carboxylate

HRID 1506901노트

반응식

HRID 1506901 반응식
[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]3[CH2:16][CH2:17]C[CH2:19][C:13]=3[C:12]=2[C:20]([O:22][CH2:23]C)=[O:21])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.NC1SC(CC)=C(C)C=1C(OC)=O.C1(S(Cl)(=O)=O)C=CC=CC=1>>[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]([CH2:16][CH3:17])=[C:13]([CH3:19])[C:12]=2[C:20]([O:22][CH3:23])=[O:21])(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 7369Benzenesulfonyl chlorideHCID 391240Ethyl 2-(benzenesulfonamido)-4,5,6,7-tetrahydrobenzothiophene-3-carboxylateHCID 4715118Methyl 2-amino-5-ethyl-4-methylthiophene-3-carboxylate

생성물 1

HCID 68278735Methyl 2-benzenesulphonylamino-5-ethyl-4-methylthiophene-3-carboxylate

실험 절차

Prepared by proceeding in a similar manner to Intermediate 1, starting from methyl 2-amino-5-ethyl-4-methylthiophene-3-carboxylate and benzenesulphonyl chloride.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-3e6f67c0c939441b9be17c6269b01a61
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09221787B2

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