Benzenesulfonyl chloride → Methyl 2-benzenesulphonylamino-4-methyl-5-phenylthiophene-3-carboxylate

HRID 1506904노트

반응식

HRID 1506904 반응식
[C:1]1([S:7](NC2SC3CCCCC=3C=2C(OCC)=O)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:25][C:26]1[S:27][C:28]([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)=[C:29]([CH3:35])[C:30]=1[C:31]([O:33][CH3:34])=[O:32].C1(S(Cl)(=O)=O)C=CC=CC=1>>[C:1]1([S:7]([NH:25][C:26]2[S:27][C:28]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[C:29]([CH3:35])[C:30]=2[C:31]([O:33][CH3:34])=[O:32])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 3

HCID 7369Benzenesulfonyl chlorideHCID 391240Ethyl 2-(benzenesulfonamido)-4,5,6,7-tetrahydrobenzothiophene-3-carboxylateHCID 921213Methyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate

생성물 1

HCID 68278826Methyl 2-benzenesulphonylamino-4-methyl-5-phenylthiophene-3-carboxylate

실험 절차

Prepared by proceeding in a similar manner to Intermediate 1, starting from methyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate and benzenesulphonyl chloride

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-cbad8fd97f7d4cde975281a6474fe372
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09221787B2

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