Benzenesulfonyl chloride → HCID 68278707, 화합물

HRID 1506910노트

반응식

HRID 1506910 반응식
[C:1]1([S:7]([NH:10][C:11]2[S:15][C:14]3[CH2:16][CH2:17][CH2:18][CH2:19][C:13]=3[C:12]=2[C:20]([O:22][CH2:23][CH3:24])=[O:21])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.N[C:26]1SC2CCC(C)CC=2C=1C(OCC)=O.C1(S(Cl)(=O)=O)C=CC=CC=1>>[CH3:26][CH:18]1[CH2:17][CH2:16][C:14]2[S:15][C:11]([NH:10][S:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)(=[O:9])=[O:8])=[C:12]([C:20]([O:22][CH2:23][CH3:24])=[O:21])[C:13]=2[CH2:19]1

참가 물질

4

반응물 3

HCID 7369Benzenesulfonyl chlorideHCID 391240Ethyl 2-(benzenesulfonamido)-4,5,6,7-tetrahydrobenzothiophene-3-carboxylateHCID 402542Ethyl 2-amino-5-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

생성물 1

HCID 68278707HCID 68278707, 화합물

실험 절차

Prepared by proceeding in a similar manner to Intermediate 1, starting from ethyl 2-amino-5-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (prepared according to Pinkerton et al., Bioorg. Med. Chem. Lett., 2007, 17, 3562-3569) and benzenesulphonyl chloride.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-b2080c36e2cb47c8b1b3bd0f5e0dbeb0
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09221787B2

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