Nicotinic Acid → HCID 73427146, 화합물

반응식

[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.[NH2:10][C:11]1[CH:19]=[C:18]2[C:14]([C:15]([CH3:23])([CH3:22])[C:16](=[O:21])[N:17]2[CH3:20])=[CH:13][CH:12]=1>>[CH3:20][N:17]1[C:18]2[C:14](=[CH:13][CH:12]=[C:11]([NH:10][C:1](=[O:9])[C:2]3[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=3)[CH:19]=2)[C:15]([CH3:22])([CH3:23])[C:16]1=[O:21]

참가 물질

반응물 2

HCID 938Nicotinic Acid

HCID 529112486-Amino-1,3,3-trimethyl-1,3-dihydro-2H-indol-2-one

생성물 1

HCID 73427146HCID 73427146, 화합물

실험 절차

Prepared in analogy to example 1b from nicotinic acid and 6-amino-1,3,3-trimethylindolin-2-one (W. von der Saal et al., J. Med. Chem. 1989, 32(7), 1481-1491). The title compound was obtained as light yellow solid.

출처 및 근거

ORD 기록: ord-8e294dee14ce4679aa21b9ecfb592e6d
출처 데이터셋: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09221816B2

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