1,4-Dioxane → N-(4-(Trifluoromethyl)phenyl)-5,6,7,8-tetrahydro-7-(3-(methylsulfonyl)pyridin-2-yl)-2-(methylthio)pyrido[3,4-d]pyrimidin-4-amine

반응식

[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[Cl:24][c:25]1[n:26][cH:27][cH:28][cH:29][c:30]1[S:31](=[O:32])(=[O:33])[CH3:34].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([NH:9][c:10]2[c:11]3[c:12]([n:13][c:14]([S:16][CH3:17])[n:15]2)[CH2:18][NH:19][CH2:20][CH2:21]3)[cH:7][cH:8]1)([F:22])[F:23].[O:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49]1>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([NH:9][c:10]2[c:11]3[c:12]([n:13][c:14]([S:16][CH3:17])[n:15]2)[CH2:18][N:19]([c:25]2[n:26][cH:27][cH:28][cH:29][c:30]2[S:31](=[O:32])(=[O:33])[CH3:34])[CH2:20][CH2:21]3)[cH:7][cH:8]1)([F:22])[F:23]