Sodium Hydroxide → HCID 61834499, 화합물

반응식

[CH3:1][C:2]1[CH:3]=[C:4]([NH:16]C(=O)C)[CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)=[O:9].[OH-].[Na+]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[C:8]([N:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)=[O:9])[NH2:16]

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 68637681N-[3-methyl-4-(morpholin-4-yl-carbonyl)-phenyl]-acetamide

생성물 1

HCID 61834499HCID 61834499, 화합물

반응 조건

온도: 65 °C

실험 절차

700.0 mg (2.67 mmol) N-[3-methyl-4-(morpholin-4-yl-carbonyl)-phenyl]-acetamide are combined with 7 ml 4-molar sodium hydroxide solution and stirred overnight at 65° C. The reaction mixture is poured onto ice water and extracted with ethyl acetate. The organic phase is dried over magnesium sulphate and evaporated down i. vac.

후처리

additionThe reaction mixture is poured onto ice water
extractionextracted with ethyl acetate
dry with materialThe organic phase is dried over magnesium sulphate
customevaporated down i

출처 및 근거

ORD 기록: ord-0aa6374f81f648318495f33d600113bb
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07732466B2

반응 노트

불러오는 중…