Lithium hydroxide, monohydrate → 2-(6-Ethynyl-2-oxoquinolin-1(2H)-yl)acetic acid
반응식
[O:1]=[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:12]#[C:13][Si](C)(C)C)[CH:8]=2)[N:3]1[CH2:18][C:19]([O:21]C)=[O:20].O[Li].O>>[C:12]([C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]([CH2:18][C:19]([OH:21])=[O:20])[C:2](=[O:1])[CH:11]=[CH:10]2)#[CH:13]참가 물질
3
실험 절차
Methyl 2-(2-oxo-6-((trimethylsilyl)ethynyl)quinolin-1(2H)-yl)acetate (0.128 mmol) was subjected to the protocol in Example 1.53.4, except with LiOH.H2O instead of NaOH. Retention time (min)=1.435, method [1], MS(ESI) 228.1 (M+H).
출처 및 근거
- ORD 기록
- ord-3b3b058665884ae88bd93b95cf9e205a
- 출처 데이터셋
- uspto-grants-2015_07
- 특허 번호
- US09073891B2
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