Acryloyl chloride → N-(5-((6-amino-5-(4-(4-cyanophenoxy)phenyl)pyrimidin-4-yl)oxy)pyridin-3-yl)acrylamide

반응식

Cl[C:2]1[C:3]([NH2:9])=[N:4][CH:5]=[N:6][C:7]=1Cl.Cl.Cl.[NH2:12][C:13]1[CH:14]=[C:15]([OH:19])[CH:16]=[N:17][CH:18]=1.CC1(C)C(C)(C)OB([C:28]2[CH:42]=[CH:41][C:31]([O:32][C:33]3[CH:40]=[CH:39][C:36]([C:37]#[N:38])=[CH:35][CH:34]=3)=[CH:30][CH:29]=2)O1.[C:44](Cl)(=[O:47])[CH:45]=[CH2:46]>>[NH2:9][C:3]1[N:4]=[CH:5][N:6]=[C:7]([O:19][C:15]2[CH:14]=[C:13]([NH:12][C:44](=[O:47])[CH:45]=[CH2:46])[CH:18]=[N:17][CH:16]=2)[C:2]=1[C:28]1[CH:42]=[CH:41][C:31]([O:32][C:33]2[CH:40]=[CH:39][C:36]([C:37]#[N:38])=[CH:35][CH:34]=2)=[CH:30][CH:29]=1