Hydrogen Bromide → (R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

HRID 1523

반응식

HRID 1523 반응식
C[O:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[O:9]C.[BrH:15]>>[BrH:15].[OH:2][C:3]1[CH:4]=[C:5]([CH2:11][C@H:12]([NH2:14])[CH3:13])[CH:6]=[CH:7][C:8]=1[OH:9]

참가 물질

3

반응물 2

HCID 260Hydrogen BromideHCID 117694083,4-Dma, (R)-

생성물 1

HCID 67643451(R)-3-(3,4-Dihydroxyphenyl)-2-propylamine hydrobromide

실험 절차

A solution of (R)-3-(3,4-dimethoxyphenyl)-2-propylamine hydrochloride1 (500 mg, 2.15 mMol) in hydrogen bromide (48%, 5 ml) was stirred at 100° C. under an argon atmosphere for 20 hours. After cooling, the solvent was evaporated and the residue was dried giving the title compound.

후처리

  1. temperatureAfter cooling
  2. customthe solvent was evaporated
  3. customthe residue was dried

출처 및 근거

ORD 기록
ord-a3c93df638364213adea34d2adfb06d5
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05726165

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