Sodium Hydroxide → 2-Butyloctanoic acid

HRID 1525627노트

반응식

HRID 1525627 반응식
[CH2:1]([C:5](CCCC)([C:14]([OH:16])=[O:15])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])[CH2:2][CH2:3][CH3:4].[OH-].[Na+]>>[CH2:1]([CH:5]([C:14]([OH:16])=[O:15])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])[CH2:2][CH2:3][CH3:4]

참가 물질

3

반응물 2

HCID 14798Sodium HydroxideHCID 23166994HCID 23166994, 화합물2회

생성물 1

HCID 64522882-Butyloctanoic acid

실험 절차

The above chiral salt, an organic solvent, an alkaline aqueous medium, and dibutyl 1,6-dicarboxy-hexane are mixed in a vessel. 1.0 equivalents (based upon the moles and equivalents of dibutyl 1,6-dicarboxy-hexane) of alkalizing agent, such as sodium hydroxide, is added, optionally with heating. The hydrolysis is allowed to proceed to completion. The mono-esterified butyl 1,6-dicarboxy-hexane is contained within the aqueous phase. The phases are separated. The aqueous phase is acidified with dilute acid to pH 4.5 with cooling. The butyl 1,6-dicarboxy-hexane is isolated by filtration or extraction with diethyl ether.

후처리

  1. temperatureoptionally with heating
  2. customThe phases are separated
  3. additionwith dilute acid to pH 4.5
  4. temperaturewith cooling

출처 및 근거

ORD 기록
ord-c90fac2c5380448eb09d6b87dd63e126
출처 데이터셋
uspto-grants-2015_07
특허 번호
US09085525B2

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