Iodoethane → HCID 178462537, 화합물

반응식

[CH3:1][C:2]1[O:3][C:4]2[C:5]([N:10]=1)=[N:6][CH:7]=[CH:8][CH:9]=2.[CH2:11]([I:13])[CH3:12]>>[I-:13].[CH2:11]([N:6]1[CH:7]=[CH:8][CH:9]=[C:4]2[O:3][CH:2]([CH3:1])[NH+:10]=[C:5]12)[CH3:12]

참가 물질

반응물 2

HCID 6340Iodoethane

HCID 14821822-Methyloxazolo[4,5-b]pyridine

생성물 1

HCID 178462537HCID 178462537, 화합물수율 86%

실험 절차

This Example shows the preparation of exemplary compound Dye 9 and its physical properties. A mixture of 1.34 g (10 mmol) 2-methyl-oxazolo[4,5-b]pyridine and 2 ml ethyliodide in a closed system was kept 2 h at 110° C. The product was precipitated with acetone and filtered off. The yellow crystalline product was filtered off and washed with diethyl ether to provide 2.47 g (86%) 4-ethyl-2-methyl-oxazolo[4,5-b]pyridinium iodide, which was of sufficient purity to carry on to the next synthetic step.

후처리

customthe preparation of exemplary compound Dye 9 and its physical properties
customThe product was precipitated with acetone
filtrationfiltered off
filtrationThe yellow crystalline product was filtered off
washwashed with diethyl ether

출처 및 근거

ORD 기록: ord-66cdb5ebfaa346b08f45f5cb3a0c2935
출처 데이터셋: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09085698B2

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