Acetic Anhydride → 3-Methyl-4-acetoxybenzofuran
반응식
[CH3:1][C:2]1[C:6]2[C:7]([OH:11])=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][CH:3]=1.[C:12](OC(=O)C)(=[O:14])[CH3:13].C(N(CC)CC)C>O1CCCC1>[CH3:1][C:2]1[C:6]2[C:7]([O:11][C:12](=[O:14])[CH3:13])=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][CH:3]=1참가 물질
5
실험 절차
A solution of 3-methyl-4-hydroxybenzofuran (5.0 gm, 34.7 mmoles), acetic anhydride (50 mL) and triethylamine (25 mL) in tetrahydrofuran (150 mL) was stirred at room temperature overnight. The volatiles were removed in vacuo and the residue was purified by chromatography on silica gel. Elution with 15% ethylacetate in hexane yielded 3-methyl-4-acetoxybenzofuran.
후처리
- customThe volatiles were removed in vacuo
- customthe residue was purified by chromatography on silica gel
- washElution with 15% ethylacetate in hexane
출처 및 근거
- ORD 기록
- ord-1b21741b5e734ad4acd38b85fcc73a3a
- 출처 데이터셋
- uspto-grants-1992_02
- 특허 번호
- US05087638
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