Sodium Bicarbonate → (3,3-Diethoxy-propyl)-carbamic acid allyl ester
반응식
[C:1](Cl)(=[O:5])[CH2:2][CH:3]=C.[CH2:7]([O:9][CH:10]([O:14][CH2:15][CH3:16])[CH2:11][CH2:12][NH2:13])[CH3:8].[C:17]([O-])(O)=[O:18].[Na+]>C(Cl)Cl>[CH2:2]([O:3][C:17](=[O:18])[NH:13][CH2:12][CH2:11][CH:10]([O:14][CH2:15][CH3:16])[O:9][CH2:7][CH3:8])[CH:1]=[CH2:5]참가 물질
5
실험 절차
But-3-enoyl chloride (930 uL, 8.84 mmol) was added slowly to a rapidly stirring mixture of 3,3-diethoxy-propylamine (1.0 g, 6.80 mmol) and NaHCO3 (2 mL of 0.6 M NaHCO3 in water) in DCM (100 mL). The reaction was stirred at room temperature overnight, then partitioned between water and DCM. The organic layer was washed several times with water and concentrated to give the crude sub-title compound that was used without further purification.
후처리
- stirringThe reaction was stirred at room temperature overnight
- custompartitioned between water and DCM
- washThe organic layer was washed several times with water
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-233d52f44e6349a7a7bc1dd57e6b77de
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07732618B2
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