Dimethylformamide → Tert-butyl 1'-(5-bromopyrazin-2-yl)-4,4'-bipiperidine-1-carboxylate

반응식

[Br:26][N:27]1[C:28](=[O:29])[CH2:30][CH2:31][C:32]1=[O:33].[O:34]=[CH:35][N:36]([CH3:37])[CH3:38].[n:1]1[c:2]([N:7]2[CH2:8][CH2:9][CH:10]([CH:13]3[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[CH2:11][CH2:12]2)[cH:3][n:4][cH:5][cH:6]1>>[n:1]1[c:2]([N:7]2[CH2:8][CH2:9][CH:10]([CH:13]3[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[CH2:11][CH2:12]2)[cH:3][n:4][c:5]([Br:26])[cH:6]1

참가 물질

반응물 3

HCID 6228Dimethylformamide

HCID 67184N-bromobutanimide

HCID 54581959Tert-butyl 1'-pyrazin-2-yl-4,4'-bipiperidine-1-carboxylate

생성물 1

HCID 59178948Tert-butyl 1'-(5-bromopyrazin-2-yl)-4,4'-bipiperidine-1-carboxylate

출처 및 근거

ORD 기록: ord-331d9472a11e454aa4614e8abb7cd6be
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…