Tetrahydrofuran → Methyl 5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)-2-(3,4-difluorophenyl)-3-oxo-2,3-dihydrofuro[2,3-b]pyridine-2-carboxylate

반응식

[CH2:50]1[CH2:53][CH2:52][CH2:51][O:54]1.[CH3:38][Si:39]([NH-:40])([CH3:41])[CH3:42].[CH3:43][Si:44]([NH-:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([C:36]#[N:37])[c:11]([O:22][CH:23]([C:24](=[O:25])[O:26][CH3:27])[c:28]3[cH:29][c:30]([F:35])[c:31]([F:34])[cH:32][cH:33]3)[n:12][c:13]2-[c:14]2[c:15]([Cl:21])[cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:6][cH:7]1.[Li+:48].[Li+:49]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]3[c:11]([n:12][c:13]2-[c:14]2[c:15]([Cl:21])[cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[O:22][C:23]([C:24](=[O:25])[O:26][CH3:27])([c:28]2[cH:29][c:30]([F:35])[c:31]([F:34])[cH:32][cH:33]2)[C:36]3=[O:54])[cH:6][cH:7]1