2-Methoxypyrimidine-5-boronic acid → [2,6-Difluoro-4-(2-methoxypyrimidin-5-yl)phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

HRID 1573166

반응식

HRID 1573166 반응식
[Br:1][c:2]1[cH:3][c:4]([F:22])[c:5]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[c:6]([F:8])[cH:7]1.[CH3:23][O:24][c:25]1[n:26][cH:27][c:28]([B:31]([OH:32])[OH:33])[cH:29][n:30]1>>[c:2]1(-[c:28]2[cH:27][n:26][c:25]([O:24][CH3:23])[n:30][cH:29]2)[cH:3][c:4]([F:22])[c:5]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[c:6]([F:8])[cH:7]1

참가 물질

3

반응물 2

HCID 27367782-Methoxypyrimidine-5-boronic acidHCID 11964889(4-Bromo-2,6-difluorophenyl)-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

생성물 1

HCID 11611075[2,6-Difluoro-4-(2-methoxypyrimidin-5-yl)phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

출처 및 근거

ORD 기록
ord-411857ba6cc34776b257a9976cb75edb
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

연결된 노트

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