Potassium Cation → 2-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-5-({6-[(2-hydroxy-2-methylpropoxy)methyl]pyridin-2-yl}amino)-1,3-thiazole-4-carboxamide

HRID 1573906노트

반응식

[Br:22][c:23]1[cH:24][cH:25][cH:26][c:27]([CH2:29][O:30][CH2:31][C:32]([CH3:33])([OH:34])[CH3:35])[n:28]1.[C:36](=[O:37])([O-:38])[O-:39].[K+:40].[K+:41].[NH2:1][c:2]1[c:3]([C:19](=[O:20])[NH2:21])[n:4][c:5](-[c:7]2[c:8]([F:18])[cH:9][c:10]([C:14]([CH3:15])([CH3:16])[OH:17])[cH:11][c:12]2[F:13])[s:6]1.[O:44]=[C:45]([CH:46]=[CH:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1)[CH:54]=[CH:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1.[O:62]=[C:63]([CH:64]=[CH:65][c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1)[CH:72]=[CH:73][c:74]1[cH:75][cH:76][cH:77][cH:78][cH:79]1.[O:80]=[C:81]([CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1)[CH:90]=[CH:91][c:92]1[cH:93][cH:94][cH:95][cH:96][cH:97]1.[Pd:42].[Pd:43]>>[NH:1]([c:2]1[c:3]([C:19](=[O:20])[NH2:21])[n:4][c:5](-[c:7]2[c:8]([F:18])[cH:9][c:10]([C:14]([CH3:15])([CH3:16])[OH:17])[cH:11][c:12]2[F:13])[s:6]1)[c:23]1[cH:24][cH:25][cH:26][c:27]([CH2:29][O:30][CH2:31][C:32]([CH3:33])([OH:34])[CH3:35])[n:28]1