N,N-dimethyl-3-(pyridin-3-yl)propan-1-amine → 1-(9-Xanthenyl)-3-[3-(dimethylamino)propyl]piperidine

HRID 1576401노트

반응식

HRID 1576401 반응식
C(O[CH:5]1[C:18]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[O:12][C:11]2[C:6]1=[CH:7][CH:8]=[CH:9][CH:10]=2)(=O)C.[CH3:19][N:20]([CH3:30])[CH2:21][CH2:22][CH2:23][CH:24]1[CH2:29][CH2:28][CH2:27][NH:26][CH2:25]1.CN(C)CCCC1C=NC=CC=1>[Ru](=O)=O>[CH:7]1[C:6]2[CH:5]([N:26]3[CH2:27][CH2:28][CH2:29][CH:24]([CH2:23][CH2:22][CH2:21][N:20]([CH3:30])[CH3:19])[CH2:25]3)[C:18]3[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=3)[O:12][C:11]=2[CH:10]=[CH:9][CH:8]=1

참가 물질

5

반응물 3

HCID 238309N,N-dimethyl-3-(pyridin-3-yl)propan-1-amineHCID 125434549-AcetoxyxantheneHCID 15057302Dimethyl[3-(piperidin-3-yl)propyl]amine

생성물 1

HCID 215125741-(9-Xanthenyl)-3-[3-(dimethylamino)propyl]piperidine

시약·촉매·용매 1

HCID 82848Ruthenium dioxide촉매

실험 절차

By the procedure of Example 1, reacting 9-acetoxyxanthene with 3-(3-dimethylaminopropyl)piperidine [prepared by hydrogenating 3-(3-dimethylaminopropyl)pyridine in the presence of ruthenium dioxide by the procedure of Example 12] gives 1-(9-xanthenyl)-3-[3-(dimethylamino)propyl]piperidine.

출처 및 근거

ORD 기록
ord-7107256773c54988a1f8aec5d14e8d69
출처 데이터셋
uspto-grants-1976_09
특허 번호
US03980788

반응 노트

불러오는 중…