Hydrochloric Acid → HCID 54500173, 화합물

HRID 1576588노트

반응식

HRID 1576588 반응식
[CH3:1][C:2]([CH:7]=[CH:8][CH2:9][CH:10]([CH3:19])[CH2:11][CH2:12][CH2:13][C:14]([CH3:18])([CH3:17])[CH2:15][CH3:16])=[CH:3][C:4]([OH:6])=O.[CH3:20][CH2:21]OCC.C([Li])C.Cl>C1C=CC=CC=1>[CH3:1][C:2]([CH:7]=[CH:8][CH2:9][CH:10]([CH3:19])[CH2:11][CH2:12][CH2:13][C:14]([CH3:18])([CH3:17])[CH2:15][CH3:16])=[CH:3][C:4](=[O:6])[CH2:20][CH3:21]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 54353726HCID 54353726, 화합물HCID 178506846HCID 178506846, 화합물

생성물 1

HCID 54500173HCID 54500173, 화합물

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

To a stirred solution of 2.5 g. of 3,7,11,11-tetramethyltrideca-2,4-dienoic acid in 30 ml. of dry ether is added slowly, at 0°, 23 ml. of a one molar solution of ethyl lithium in benzene. After about three hours at 20°, the mixture is poured into iced 1N hydrochloric acid (100 ml.) with vigorous stirring. The ether layer is separated, combined with ethereal washings of the aqueous phase, washed with water, saturated potassium bicarbonate, and then saturated brine, dried over magnesium sulfate and concentrated under reduced pressure to yield 5,9,13,13-tetramethylpentadeca-4,6-dien-3-one which is purified by high vacuum distillation or chromatography.

후처리

  1. customThe ether layer is separated
  2. washwashed with water, saturated potassium bicarbonate
  3. dry with materialsaturated brine, dried over magnesium sulfate
  4. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-fc87498485f34528a6a22bba822f5af6
출처 데이터셋
uspto-grants-1976_09
특허 번호
US03981922

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