[NH2:1][CH2:2][CH:3]([OH:11])[C:4]1[CH:9]=[CH:8][C:7]([F:10])=[CH:6][CH:5]=1.C1(C)C(C)=CC=CC=1.N([C:24]1[NH:25][CH2:26][CH2:27][N:28]=1)[N+]([O-])=O.C1C=CC=CC=1>CC(C)=O>[F:10][C:7]1[CH:8]=[CH:9][C:4]([CH:3]([OH:11])[CH2:2][NH:1][C:24]2[NH:28][CH2:27][CH2:26][N:25]=2)=[CH:5][CH:6]=1To a solution of 6.5 parts of α-(aminomethyl)-p-fluorobenzyl alcohol in 8 parts of xylene are added 5.2 parts of 2-(nitramino)-2-imidazoline. The mixture is heated in an oil-bath to about 160°C. till gas-evolution is ceased (about 15 minutes). The reaction mixture is cooled and treated with benzene and acetone. The product is sucked off and crystallized from 4-methyl-2-pentanone, yielding p-fluoro-α-(2-imidazolin-2-ylaminomethyl)benzyl alcohol; m.p. 153.4°C.
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