Dimethylamine → N-((Dimethylamino)methyl)acrylamide
반응식
C=O.C(N)(=O)C=C.[OH-].[Na+].[CH2:10]([NH:12][C:13](=[O:16])[CH:14]=[CH2:15])O.[CH3:17][NH:18][CH3:19]>>[CH3:17][N:18]([CH2:10][NH:12][C:13](=[O:16])[CH:14]=[CH2:15])[CH3:19]참가 물질
6
반응 조건
- 온도
- 65 °C
실험 절차
Into a reaction vessel as employed in Example 1 is added 13.3 parts of paraformaldehyde and 62.9 parts of a 48.1% aqueous solution of acrylamide. The pH is adjusted with aqueous NaOH to 11.5 and the homogeneous mixture allowed to stand 24 hours at room temperature. The product, >90 mole percent converted N-methylolacrylamide, is acidified to a pH of 2 and to it is added 57.5 parts of a 40% dimethylamine aqueous solution acidified to a pH of 2. The resulting solution is heated 3 hours at 65° C. and yields about 50 mole percent of N-(dimethylaminomethyl)acrylamide.
후처리
- customInto a reaction vessel as employed in Example 1
출처 및 근거
- ORD 기록
- ord-f0fb98faf5ae4834b5f43f85cb50ecc6
- 출처 데이터셋
- uspto-grants-1981_09
- 특허 번호
- US04288390
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