Hydrochloric Acid → 2-Hydroxynonanedioic acid
반응식
Br[CH:2]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([O:15]C)=[O:14])[C:3]([O:5]C)=[O:4].C(=O)([O-])[O-:18].[Na+].[Na+].Cl.[Cl-].[Na+]>O>[OH:18][CH:2]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])[C:3]([OH:5])=[O:4]참가 물질
6
실험 절차
A stirred mixture of 295 g. of dimethyl 2-bromononanedioate, [Acta. Chim. Acad. Sci. Hung., 46, 85 (1965)], 371 g. of anhydrous sodium carbonate, and 3 liters of water is heated at reflux for 22 hours. The solution which forms is cooled and acidified with 600 ml. of 12 N hydrochloric acid. The mixture is saturated with sodium chloride and extracted with ethyl acetate. The extract is washed with brine, dried over magnesium sulfate, and concentrated to give 184 g. of white solid, m.p. 86°-92° C.
후처리
- additionA stirred mixture of 295 g
- temperatureat reflux for 22 hours
- temperatureThe solution which forms is cooled
- extractionextracted with ethyl acetate
- washThe extract is washed with brine
- dry with materialdried over magnesium sulfate
- concentrationconcentrated
- customto give 184 g
출처 및 근거
- ORD 기록
- ord-5c5e5202ac7a4ad98783b20bf08461c4
- 출처 데이터셋
- uspto-grants-1981_09
- 특허 번호
- US04288630
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