Benzylamine → 75484-74-1

HRID 1577801노트

반응식

HRID 1577801 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([CH3:9])[C:3]=1[N+:10]([O-:12])=[O:11].[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)(C)C>[ClH:1].[CH2:13]([NH:20][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([CH3:9])[C:3]=1[N+:10]([O-:12])=[O:11])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

4

반응물 2

HCID 7504BenzylamineHCID 107027254-Chloro-2,6-dimethyl-3-nitropyridine

생성물 1

HCID 2056958975484-74-1

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

9.3 Grams (0.05 mol) of 4-chloro-2,6-dimethyl-3-nitropyridine and 10.7 g (0.1 mol) of benzylamine are heated for 5 hours at boiling point in 20 ml of isopropanol. After cooling, the mixture is concentrated, dissolved in water and extracted with chloroform. The chloroform phase is dried with sodium sulfate and concentrated. The residue is converted with ethanolic hydrochloric acid into the hydrochloride and recrystallized from isopropanol.

후처리

  1. temperatureAfter cooling
  2. concentrationthe mixture is concentrated
  3. dissolutiondissolved in water
  4. extractionextracted with chloroform
  5. dry with materialThe chloroform phase is dried with sodium sulfate
  6. concentrationconcentrated
  7. customrecrystallized from isopropanol

출처 및 근거

ORD 기록
ord-29a122e524ff4855ad8c54d9ee8de13d
출처 데이터셋
uspto-grants-1981_09
특허 번호
US04289765

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