Hydrogen Peroxide → Cyclopentane, 1-acetyl-1,2-epoxy-

HRID 1578807

반응식

HRID 1578807 반응식
[C:1]([C:4]1[CH2:8][CH2:7][CH2:6][CH:5]=1)(=[O:3])[CH3:2].[OH:9]O.[OH-].[Na+]>CO.O>[C:1]([C:4]12[O:9][CH:5]1[CH2:6][CH2:7][CH2:8]2)(=[O:3])[CH3:2]

참가 물질

6

반응물 3

HCID 784Hydrogen PeroxideHCID 14798Sodium HydroxideHCID 1929251-Acetylcyclopentene

생성물 1

HCID 537123Cyclopentane, 1-acetyl-1,2-epoxy-

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

A solution of 11.02 g of 1-acetyl-cyclopent-1-ene in 50 ml of methanol is cooled to -10°C and mixed with 28.8 ml of perhydrol within 5 minutes. In the course of 1 hour, while stirring and cooling, 8.25 ml of 6N-sodium hydroxide solution are added, the whole is stirred for 1/2 hour at room temperature, diluted with 125 ml of water and extracted with pentane. The pentane solution is washed neutral with sodium chloride solution and the pentane is distilled off through a Vigreux column. The residue is distilled under 10 mm Hg pressure, to yield 1-acetyl-1,2-epoxy-cyclopentane passing over at 62° - 63°C.

후처리

  1. temperaturecooling
  2. stirringthe whole is stirred for 1/2 hour at room temperature
  3. extractionextracted with pentane
  4. washThe pentane solution is washed neutral with sodium chloride solution
  5. distillationthe pentane is distilled off through a Vigreux column
  6. distillationThe residue is distilled under 10 mm Hg pressure

출처 및 근거

ORD 기록
ord-c72dce79878e4d71943d180cc5d16560
출처 데이터셋
uspto-grants-1976_02
특허 번호
US03939207

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