Hydrochloric Acid → HCID 21567166, 화합물

반응식

[CH3:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[C:9]([N+:12]([O-:14])=[O:13])[CH:8]=[CH:7][CH:6]=2.[ClH:15]>>[ClH:15].[CH3:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[C:9]([N+:12]([O-:14])=[O:13])[CH:8]=[CH:7][CH:6]=2

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 2749733-Methyl-5-nitroisoquinoline

생성물 1

HCID 21567166HCID 21567166, 화합물

실험 절차

3-methyl-5-nitro-isoquinoline (6 g), prepared according to the method of Example 5 hereinabove, was dissolved in concentrated hydrochloric acid (30 ml). The excess acid was then removed by means of a rotary evaporator, and the residue was digested with boiling ethanol (100 ml). The mixture was cooled and filtered, and the residue was dried in vacuo for several hours, to yield 6.9 g of 3-methyl-5-nitro-isoquinoline hydrochloride melting over a temperature range from 178° to 183°C.

후처리

customThe excess acid was then removed by means of a rotary evaporator
temperatureThe mixture was cooled
filtrationfiltered
customthe residue was dried in vacuo for several hours

출처 및 근거

ORD 기록: ord-9ee6f02f5fed4ac4bb2c56c65cb2fe69
출처 데이터셋: uspto-grants-1976_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03930837

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