HCID 73796369, 화합물 → 5-Oxo-5H-chromeno[2,3-B]pyridine-7-carbonitrile

HRID 1579383노트

반응식

HRID 1579383 반응식
[O:1]=[C:2]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][CH:10]=2)[O:5][C:4]2[CH:12]=[CH:13][C:14]([CH:16]=[N:17]O)=[CH:15][C:3]1=2>C(OC(=O)C)(=O)C>[O:1]=[C:2]1[C:11]2[C:6](=[N:7][CH:8]=[CH:9][CH:10]=2)[O:5][C:4]2[CH:12]=[CH:13][C:14]([C:16]#[N:17])=[CH:15][C:3]1=2

참가 물질

3

반응물 1

HCID 73796369HCID 73796369, 화합물

생성물 1

HCID 128984545-Oxo-5H-chromeno[2,3-B]pyridine-7-carbonitrile

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

A mixture of 25 g of 5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-7-carbaldehyde oxime and 150 ml of acetic anhydride is stirred under reflux for 24 hours. After cooling, the crystals are filtered off, washed with water, dried, and recrystallized from dimethylformamide to give 5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-7-carbonitrile melting at 260°C.

후처리

  1. temperatureunder reflux for 24 hours
  2. temperatureAfter cooling
  3. filtrationthe crystals are filtered off
  4. washwashed with water
  5. customdried
  6. customrecrystallized from dimethylformamide

출처 및 근거

ORD 기록
ord-0400201aed50485d8dc96749cdd9fc34
출처 데이터셋
uspto-grants-1976_01
특허 번호
US03931199

반응 노트

불러오는 중…