Ethanol → 1-Amino-2-nitro-4-omega-cyanoacetylamino-benzene

HRID 1580769노트

반응식

HRID 1580769 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].C(O)C.[C:15]([CH2:17][C:18](OCC)=[O:19])#[N:16]>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:18](=[O:19])[CH2:17][C:15]#[N:16])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

참가 물질

4

반응물 3

HCID 702EthanolHCID 7764Ethyl cyanoacetateHCID 43383702-Nitro-4-phenylenediamine

생성물 1

HCID 203760951-Amino-2-nitro-4-omega-cyanoacetylamino-benzene

실험 절차

15.3 gm (0.1 mol) of 1,4-diamino-2-nitrobenzene were heated to boiling in 150 ml of ethyl cyanoacetate. Simultaneously therewith the ethanol formed during the reaction was removed by distillation. After the reaction mixture was cooled, the precipitate formed was vacuum filtered, washed with ether and recrystallized from dilute acetic acid. The product had a melting point of 218°-221°C.

후처리

  1. customwas removed by distillation
  2. temperatureAfter the reaction mixture was cooled
  3. customthe precipitate formed
  4. filtrationfiltered
  5. washwashed with ether
  6. customrecrystallized from dilute acetic acid

출처 및 근거

ORD 기록
ord-33eddbc218fb477985b9c89771e72f12
출처 데이터셋
uspto-grants-1976_01
특허 번호
US03933886

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