N-acetoacetylaspartic acid → N-acetoacetyl-L-aspartic anhydride
반응식
[C:1]([NH:7][C@H:8]([C:13]([OH:15])=[O:14])[CH2:9][C:10]([OH:12])=O)(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4]>C(O)(=O)C.C(OC(=O)C)(=O)C>[C:1]([NH:7][C@@H:8]1[C:13](=[O:14])[O:15][C:10](=[O:12])[CH2:9]1)(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4]참가 물질
4
실험 절차
1.41 parts of N-acetoacetyl-L-aspartic acid were dissolved in 25 parts by volume of acetic acid, and 5 parts by volume of acetic anhydride were added and the mixture was stirred overnight under nitrogen. Solvent was removed under vacuum at 40°-45° C. 50 parts by volume of acetic acid were added and the evaporation repeated to form N-acetoacetyl-L-aspartic anhydride.
후처리
- additionwere added
- customSolvent was removed under vacuum at 40°-45° C
- addition50 parts by volume of acetic acid were added
- customthe evaporation
출처 및 근거
- ORD 기록
- ord-461e81ef1e1d43b7b40ed38fa6140957
- 출처 데이터셋
- uspto-grants-1985_11
- 특허 번호
- US04555362
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