N-acetoacetylaspartic acid → N-acetoacetyl-L-aspartic anhydride

HRID 1583894

반응식

HRID 1583894 반응식
[C:1]([NH:7][C@H:8]([C:13]([OH:15])=[O:14])[CH2:9][C:10]([OH:12])=O)(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4]>C(O)(=O)C.C(OC(=O)C)(=O)C>[C:1]([NH:7][C@@H:8]1[C:13](=[O:14])[O:15][C:10](=[O:12])[CH2:9]1)(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4]

참가 물질

4

반응물 1

HCID 13334672N-acetoacetylaspartic acid

생성물 1

HCID 13334674N-acetoacetyl-L-aspartic anhydride

시약·촉매·용매 2

HCID 176Acetic Acid용매HCID 7918Acetic Anhydride용매

실험 절차

1.41 parts of N-acetoacetyl-L-aspartic acid were dissolved in 25 parts by volume of acetic acid, and 5 parts by volume of acetic anhydride were added and the mixture was stirred overnight under nitrogen. Solvent was removed under vacuum at 40°-45° C. 50 parts by volume of acetic acid were added and the evaporation repeated to form N-acetoacetyl-L-aspartic anhydride.

후처리

  1. additionwere added
  2. customSolvent was removed under vacuum at 40°-45° C
  3. addition50 parts by volume of acetic acid were added
  4. customthe evaporation

출처 및 근거

ORD 기록
ord-461e81ef1e1d43b7b40ed38fa6140957
출처 데이터셋
uspto-grants-1985_11
특허 번호
US04555362

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