Hydrochloric Acid → 2-Amino-5-tert-butyl-4-(hexadecyloxy)phenol--hydrogen chloride (1/1)

HRID 1583920노트

반응식

HRID 1583920 반응식
[C:1]([C:5]1[C:14]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])=[CH:13][C:8]2[N:9]=C(C)[O:11][C:7]=2[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[ClH:32]>C(O)C>[ClH:32].[NH2:9][C:8]1[CH:13]=[C:14]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])=[CH:6][C:7]=1[OH:11]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 13076757HCID 13076757, 화합물

생성물 1

HCID 130767632-Amino-5-tert-butyl-4-(hexadecyloxy)phenol--hydrogen chloride (1/1)수율 92%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

7.3 g of the benzoxazole compound obtained in Step (d) above was refluxed for 3 hours together with 30 ml of ethanol and 20 ml of concentrated hydrochloric acid. After the completion of the reaction, the reaction mixture was allowed to stand and cool. The crystals thus precipitated were collected by filtration, washed with water and then washed with acetone. Thus, 6.9 g (92% yield) of 2-amino-5-tert-butyl-4-hexadecyloxyphenol hydrochloride was obtained.

후처리

  1. customAfter the completion of the reaction
  2. temperaturecool
  3. customThe crystals thus precipitated
  4. filtrationwere collected by filtration
  5. washwashed with water
  6. washwashed with acetone

출처 및 근거

ORD 기록
ord-9ae93751bd5944c3a27a1a3af9a0712a
출처 데이터셋
uspto-grants-1985_11
특허 번호
US04555470

반응 노트

불러오는 중…