Ethanol → 1-Chloro-4-ethoxyphthalazine

HRID 1585985노트

반응식

HRID 1585985 반응식
[Na].Cl[C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([Cl:13])=[N:5][N:4]=1.[CH2:14]([OH:16])[CH3:15]>>[CH2:14]([O:16][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([Cl:13])=[N:5][N:4]=1)[CH3:15]

참가 물질

4

반응물 3

HCID 702EthanolHCID 784901,4-DichlorophthalazineHCID 5360545Sodium

생성물 1

HCID 212176601-Chloro-4-ethoxyphthalazine

반응 조건

온도
50 °C

실험 절차

0.69 g(0.03 mol) of metallic sodium was dissolved in 100 ml of absolute ethanol and then 5.97 g(0.03 mol) of 1,4-dichlorophthalazine was added thereto and completely dissolved. The reaction solution was stirred for one hour at 50±10° C. and then treated according to the same manner as Preparation 5 to obtain the title compound as a white needle crystal.

후처리

  1. dissolutioncompletely dissolved
  2. additiontreated
  3. customaccording to the same manner as Preparation 5

출처 및 근거

ORD 기록
ord-7d5ffe21acba44a79dcdbc3ea1ab2567
출처 데이터셋
uspto-grants-1999_08
특허 번호
US05942511

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