1-(2-Hydroxyethyl)piperazine → 1-(4-Fluorobenzyl)-4-(2-Hydroxyethyl)Piperazine

반응식

[N:1]1([CH2:7][CH2:8][OH:9])[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[F:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15]Cl)=[CH:13][CH:12]=1>>[F:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15][N:4]2[CH2:5][CH2:6][N:1]([CH2:7][CH2:8][OH:9])[CH2:2][CH2:3]2)=[CH:13][CH:12]=1

참가 물질

반응물 2

HCID 76771-(2-Hydroxyethyl)piperazine

HCID 96024-Fluorobenzyl chloride

생성물 1

HCID 6938071-(4-Fluorobenzyl)-4-(2-Hydroxyethyl)Piperazine

실험 절차

The title compound was synthesized by using 2-(1-piperazinyl)ethanol and p-fluorobenzyl chloride according to the same process as in Preparation Example 4.

후처리

customas in Preparation Example 4

출처 및 근거

ORD 기록: ord-82a9b5df5a42495785edb6ec9460517d
출처 데이터셋: uspto-grants-1999_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05945434

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