Water → 1-(3-Methylphenyliminomethyl)-2-nitroiminoimidazolidine

HRID 1587735노트

반응식

HRID 1587735 반응식
C(O[CH:4](OCC)[N:5]1[CH2:9][CH2:8][NH:7][C:6]1=[N:10][N+:11]([O-:13])=[O:12])C.[NH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[CH:19]=1.C(COC)OC.O>CCOCC>[CH3:24][C:20]1[CH:19]=[C:18]([N:17]=[CH:4][N:5]2[CH2:9][CH2:8][NH:7][C:6]2=[N:10][N+:11]([O-:13])=[O:12])[CH:23]=[CH:22][CH:21]=1

참가 물질

6

반응물 4

HCID 962WaterHCID 7934m-ToluidineHCID 80711,2-DimethoxyethaneHCID 1364034191-Diethoxymethyl-2-nitroiminoimidazolidine

생성물 1

HCID 1363314831-(3-Methylphenyliminomethyl)-2-nitroiminoimidazolidine수율 51.8%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A mixture of 2.0 g of 1-diethoxymethyl-2-nitroiminoimidazolidine, 0.92 g of m-toluidine, 5 ml of dimethoxyethane and 0.12 g of a boron trifluoride ether complex was heated under reflux for 1 hour. The reaction mixture was poured into water, extracted with ethyl acetate, washed with water, dried and condensed. Ether was added to the resultant oily residue and the resultant crystals were separated by filtration and dried to give 1.1 g of 1-(3-methylphenyliminomethyl)-2-nitroiminoimidazolidine.

후처리

  1. temperaturewas heated
  2. temperatureunder reflux for 1 hour
  3. extractionextracted with ethyl acetate
  4. washwashed with water
  5. customdried
  6. customcondensed
  7. customthe resultant crystals were separated by filtration
  8. customdried

출처 및 근거

ORD 기록
ord-a8017a0832354d28a84cb41dcd8c9bb5
출처 데이터셋
uspto-grants-1993_06
특허 번호
US05219868

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