Methylhydrazine → HCID 9903609, 화합물

HRID 1588337노트

반응식

HRID 1588337 반응식
[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([C:12](=O)[CH:13]([CH3:18])[CH2:14][C:15](O)=[O:16])=[CH:11][C:5]=2[O:4][CH2:3]1.[CH3:20][NH:21][NH2:22]>C(O)C>[O:1]=[C:2]1[NH:7][C:6]2[CH:8]=[CH:9][C:10]([C:12]3[CH:13]([CH3:18])[CH2:14][C:15](=[O:16])[N:21]([CH3:20])[N:22]=3)=[CH:11][C:5]=2[O:4][CH2:3]1

참가 물질

4

반응물 2

HCID 6061MethylhydrazineHCID 11065271HCID 11065271, 화합물

생성물 1

HCID 9903609HCID 9903609, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

4-(3,4-Dihydro-3-oxo-1,4(2H)-benzoxazin-7-yl)-4-oxo-3-methylbutyric acid (1.56 g, 6.0 mmoles) was dissolved in ethanol (300 ml) and methylhydrazine (0.33 ml, 6.0 mmoles) was added. The mixture was heated at reflux for 2 hours, and then cooled to yield to yield the titled compound. The crystals were collected by filtration, recrystallized from ethanol, and recollected by filtration. The solid was dried under vacuum to yield 1.0 g of the titled compound, mp 204°-206° C.

후처리

  1. temperatureThe mixture was heated
  2. temperatureat reflux for 2 hours
  3. temperaturecooled
  4. customto yield

출처 및 근거

ORD 기록
ord-ab293ee570ac4156938e385ba76c9c40
출처 데이터셋
uspto-grants-1993_06
특허 번호
US05221742

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