Glycine → Glyphosate

반응식

[NH2:1][CH2:2][C:3]([OH:5])=[O:4].[CH:6]([P:8](=[O:11])([OH:10])[OH:9])=O.[H][H]>>[CH2:2]([NH:1][CH2:6][P:8]([OH:11])([OH:10])=[O:9])[C:3]([OH:5])=[O:4]

참가 물질

반응물 3

HCID 750Glycine2회

HCID 10154022Formylphosphonic Acid

HCID 178418361HCID 178418361, 화합물

생성물 1

HCID 3496Glyphosate수율 93.9%

실험 절차

Reaction of glycine and formylphosphonic acid was carried out in the manner described in Example 2 except that the amount of glycine used was increased slightly (1.9 g; 0.025 mole), a smaller amount of catalyst was supplied (0.1 g), and the pH was adjusted to 8.0. The system was maintained at the reaction temperature and pressure for 20 hours although hydrogen uptake ceased after 0.5 hour. The analysis indicated a 93.9% yield of glyphosate salt.