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Benzene → 2-Decanone

HRID 1589290
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HRID 1589290 반응식
[CH2:1]=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].C1C=CC=CC=1.[OH2:17]>[Cl-].C([N+](C)(C)C)CCCCCCCCCCC.O.O.[Cu](Cl)Cl.[Ru](Cl)Cl.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>[CH3:1][C:2](=[O:17])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]
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참가 물질

7

반응물 3

HCID 241BenzeneHCID 962WaterHCID 133811-Decene

생성물 1

HCID 127412-Decanone수율 64%

시약·촉매·용매 3

HCID 8152Dodecyltrimethylammonium chloride촉매HCID 61482Cupric chloride dihydrate촉매
HCID 11007548
Dichlorotris(triphenylphosphine)ruthenium
촉매

실험 절차

A mixture of copper (11) chloride dihydrate [10 mmol] and tris (triphenylphosphine) ruthenium (11) chloride [1.0 mmol] in water [10 ml] was stirred for 10 minutes at room temperature. Then 1-decene [3.51 g, 25 mmol] was added followed by benzene [15 ml] and dodecyltrimethylammonium chloride [2.0 mmol]. Oxygen was bubbled through the solution at 80° C. for 48 hours. After cooling to room temperature, ethyl acetate (15 ml) was added and the solution was filtered. The filtrate was dried using anhydrous magnesium sulphate, and then distilled to provide pure 2-decanone in 64% yield.

후처리

  1. customOxygen was bubbled through the solution at 80° C. for 48 hours
  2. temperatureAfter cooling to room temperature
  3. additionethyl acetate (15 ml) was added
  4. filtrationthe solution was filtered
  5. customThe filtrate was dried
  6. distillationdistilled

출처 및 근거

ORD 기록
ord-487f29c94b494518bfa7de0a0f2e8164
출처 데이터셋
uspto-grants-1986_02
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04568770

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