Sulfuric Acid → HCID 14249478, 화합물
반응식
[N:1]([CH2:4][CH:5]([OH:10])[CH:6]([OH:9])[CH2:7][OH:8])=[N+:2]=[N-:3].CO[C:13](OC)([CH3:15])[CH3:14].S(=O)(=O)(O)O.[OH-].[Na+]>CC(C)=O>[N:1]([CH2:4][CH:5]([CH:6]1[CH2:7][O:8][C:13]([CH3:15])([CH3:14])[O:9]1)[OH:10])=[N+:2]=[N-:3]참가 물질
6
실험 절차
A solution of 14.71 g of 4-azido-1,2,3-butanetriol in 30 ml of acetone is combined with 13.95 g of 2,2-dimethoxypropane, as well as 0.1 ml of concentrated sulfuric acid. The mixture is stirred overnight at room temperature, neutralized with 2N sodium hydroxide solution, and concentrated to dryness under vacuum. The residue is distilled with a water-jet aspirator. 2-Azido-(2,2-dimethyl-1,3-dioxolan-4-yl)ethanol passes over as a colorless oil at 130°-132° C./13 mm. Yield: 11.79 g (63% of theory).
후처리
- concentrationconcentrated to dryness under vacuum
- distillationThe residue is distilled with a water-jet aspirator
- custompasses over as a colorless oil at 130°-132° C.
출처 및 근거
- ORD 기록
- ord-c4275ce7288846a694b086c6e9121113
- 출처 데이터셋
- uspto-grants-1986_02
- 특허 번호
- US04570007
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