Ammonia → Tert-butyl 2-[[4-[2-[5-(4-chlorophenyl)-2-pyridinyl]ethynyl]anilino]methyl]pyrrolidine-1-carboxylate

HRID 158944

반응식

[CH2:46]([N:47]([CH2:48][CH3:49])[C:50](=[O:51])[c:52]1[c:53]([OH:58])[cH:54][cH:55][cH:56][cH:57]1)[CH3:59].[Cl:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[cH:18][cH:19][c:20]([C:23]#[C:24][c:25]3[cH:26][cH:27][c:28]([I:31])[cH:29][cH:30]3)[n:21][cH:22]2)[cH:15][cH:16]1.[Cu:66][I:67].[K+:7].[K+:8].[K+:9].[NH2:32][CH2:33][CH:34]1[N:35]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:36][CH2:37][CH2:38]1.[NH3:60].[O:61]=[CH:62][N:63]([CH3:64])[CH3:65].[OH2:1].[P:2]([O-:3])([O-:4])([O-:5])=[O:6]>>[Cl:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[cH:18][cH:19][c:20]([C:23]#[C:24][c:25]3[cH:26][cH:27][c:28]([NH:32][CH2:33][CH:34]4[N:35]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:36][CH2:37][CH2:38]4)[cH:29][cH:30]3)[n:21][cH:22]2)[cH:15][cH:16]1