Hydrochloric Acid → 4-Fluorobenzimidate hydrogen chloride

반응식

[F:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[ClH:10].C([OH:13])C>>[ClH:10].[F:1][C:2]1[CH:9]=[CH:8][C:5]([C:6](=[NH:7])[OH:13])=[CH:4][CH:3]=1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 702Ethanol

HCID 145174-Fluorobenzonitrile

생성물 1

HCID 1784795464-Fluorobenzimidate hydrogen chloride

실험 절차

In anhydrous ethanol, compound [I'], commercially available 4-fluorobenzonitrile is reacted with gaseous hydrogen chloride to yield compound [J'], 4-fluorobenzimidate hydrogen chloride. Compound [J'] is reacted with gaseous ammonia to yield compound [K'], 4-fluorobenzamidine hydrogen chloride.

출처 및 근거

ORD 기록: ord-080e02e70b1340468323dfe62a6de0f6
출처 데이터셋: uspto-grants-1993_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05200110

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