Glycine → HCID 13917964, 화합물

HRID 1590968노트

반응식

[NH2:1][CH2:2][C:3]([OH:5])=[O:4].[NH:6]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[C@H:7]([C:18](ON1C(=O)CCC1=O)=[O:19])[C@@H:8]([CH3:17])[O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[NH:6]([C:28]([O:30][C:31]([CH3:32])([CH3:34])[CH3:33])=[O:29])[C@H:7]([C:18]([NH:1][CH2:2][C:3]([OH:5])=[O:4])=[O:19])[C@@H:8]([CH3:17])[O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

참가 물질

반응물 2

HCID 750Glycine

HCID 12879029Boc-Thr(Bzl)-OSu

생성물 1

HCID 13917964HCID 13917964, 화합물수율 97.3%

실험 절차

By using 5.40 g of H-Gly-OH and 22.40 g of Boc-Thr(Bzl)-OSu, and the same procedure as in Reference Example 14 was repeated to obtain 19.60 g (yield: 97.3%) of the above-mentioned objective product.

출처 및 근거

ORD 기록: ord-4aee15e6777c4b0b9d95210fecd395ca
출처 데이터셋: uspto-grants-1993_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05204326

반응 노트

불러오는 중…