Methyl iodide → N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

HRID 1593346노트

반응식

HRID 1593346 반응식
[CH3:1][O:2][CH2:3][CH2:4][N:5]([CH2:8][CH3:9])[CH2:6][CH3:7].[CH3:10][I:11]>O1CCCC1>[I-:11].[CH3:1][O:2][CH2:3][CH2:4][N+:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[CH3:10]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 113555002-methoxyethyldiethylamine

생성물 1

HCID 71374868N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Next, 8.24 g of the 2-methoxyethyldiethylamine was dissolved in 10 ml of tetrahydrofuran (Wako Pure Chemical Industries), following which 4.0 ml of methyl iodide (Wako Pure Chemical Industries) was added under ice cooling. After 30 minutes, the mixture was removed from the ice bath and stirred overnight at room temperature. The solvent in the resulting reaction mixture was then driven off by vacuum distillation, and the resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)-tetrahydrofuran system, yielding 16 g of 2-methoxyethyldiethylmethylammonium iodide.

후처리

  1. additionwas added under ice cooling
  2. customthe mixture was removed from the ice bath
  3. customThe solvent in the resulting reaction mixture
  4. distillationwas then driven off by vacuum distillation
  5. customthe resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)-tetrahydrofuran system

출처 및 근거

ORD 기록
ord-c874a9245ca94705b04cdafbe3025f31
출처 데이터셋
uspto-grants-2007_11
특허 번호
US07297289B2

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