2-Methylpiperidine → HCID 21074073, 화합물

반응식

Cl[CH2:2][CH2:3][C:4]([NH:6][C:7]1[CH:20]=[CH:19][C:18]2[NH:17][C:16]3[C:11](=[CH:12][C:13]([NH:21][C:22](=[O:26])[CH2:23][CH2:24]Cl)=[CH:14][CH:15]=3)[C:10](=[O:27])[C:9]=2[CH:8]=1)=[O:5].[CH3:28][CH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][NH:30]1>>[CH3:28][CH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][N:30]1[CH2:2][CH2:3][C:4]([NH:6][C:7]1[CH:20]=[CH:19][C:18]2[NH:17][C:16]3[C:11](=[CH:12][C:13]([NH:21][C:22](=[O:26])[CH2:23][CH2:24][N:17]4[CH2:18][CH2:9][CH2:10][CH2:11][CH:16]4[CH3:15])=[CH:14][CH:15]=3)[C:10](=[O:27])[C:9]=2[CH:8]=1)=[O:5]

참가 물질

반응물 2

HCID 79742-Methylpiperidine

HCID 21074075HCID 21074075, 화합물

생성물 1

HCID 21074073HCID 21074073, 화합물

실험 절차

Chloroamide 13 (1.0 g, 2.5 mmol) was treated with 2-methylpiperidine (5 mL) according to the general aminolysis procedure to give the desired product JM-ACO-06 (916 mg, 69%) as a pale yellow/green solid.

출처 및 근거

ORD 기록: ord-e419a414c19644fdb9d877939ed2980e
출처 데이터셋: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07300930B2

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