Aluminum(III) Chloride → HCID 21707192, 화합물

HRID 1594934노트

반응식

HRID 1594934 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[C:11]([O:13]C)[CH:12]=1)[C:9](=[O:15])[CH2:8][CH2:7][CH2:6]2.[Al+3].[Cl-].[Cl-].[Cl-]>C(Cl)Cl>[OH:13][C:11]1[CH:12]=[C:3]([O:2][CH3:1])[CH:4]=[C:5]2[C:10]=1[C:9](=[O:15])[CH2:8][CH2:7][CH2:6]2

참가 물질

4

반응물 2

HCID 6451240Aluminum(III) ChlorideHCID 114470756,8-dimethoxy-3,4-dihydro-2H-naphthalen-1-one

생성물 1

HCID 21707192HCID 21707192, 화합물수율 98.6%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A solution of 6,8-dimethoxy-3,4-dihydro-2H-naphthalen-1-one (15 g, 72.8 mmole), prepared according to the procedure of J. Chem. Soc., London 2782 (1955), which is incorporated herein by reference, in methylene chloride (150 mL) at 0° C. was treated portionwise with AlCl3 (14.3 g, 107 mmole), stirred for 20 h at room temperature, poured onto ice with stirring and extracted with methylene chloride when the ice melted. The extracts were washed with water and brine, dried (MgSO4) and concentrated to provide 13.8 g of the title compound.

후처리

  1. additionpoured onto ice
  2. stirringwith stirring
  3. extractionextracted with methylene chloride when the ice
  4. washThe extracts were washed with water and brine
  5. dry with materialdried (MgSO4)
  6. concentrationconcentrated

출처 및 근거

ORD 기록
ord-d9c86aea544c469ebe9315f7aab64bf7
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06284796B1

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