Water → HCID 10126767, 화합물

HRID 1595211노트

반응식

HRID 1595211 반응식
[Mn]([O-])(=O)(=O)=[O:2].[K+].[CH3:7][O:8][C:9]1[CH:10]=[C:11]2[O:32][C:31]([CH3:34])([CH3:33])[CH:30]=[CH:29][C:12]2=[C:13]2[C:22]=1[C:21](=[O:23])[C:20]1[CH:19]=[C:18]3[CH:24]=[CH:25][CH:26]=[CH:27][C:17]3=[CH:16][C:15]=1[N:14]2[CH3:28].[OH2:35]>CC(C)=O>[O:35]=[C:29]1[C:12]2=[C:13]3[C:22](=[C:9]([O:8][CH3:7])[CH:10]=[C:11]2[O:32][C:31]([CH3:34])([CH3:33])[CH:30]1[OH:2])[C:21](=[O:23])[C:20]1[CH:19]=[C:18]2[CH:24]=[CH:25][CH:26]=[CH:27][C:17]2=[CH:16][C:15]=1[N:14]3[CH3:28]

참가 물질

5

반응물 3

HCID 962WaterHCID 516875Potassium PermanganateHCID 9799569HCID 9799569, 화합물

생성물 1

HCID 10126767HCID 10126767, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A solution of 8.1 g of potassium permanganate diluted in 30 ml of water is slowly added at room temperature to a solution of 3.5 g of the product of Example 2 in 50 ml of acetone. After 2 hours, the solution is concentrated under reduced pressure. The residue is then mixed with silica and then chromatographed on silica gel (dichloromethane/methanol: 98/2), allowing the compound of Example 4, which is present in a small amount, to be isolated from the expected product.

후처리

  1. concentrationthe solution is concentrated under reduced pressure
  2. additionThe residue is then mixed with silica
  3. customchromatographed on silica gel (dichloromethane/methanol: 98/2)

출처 및 근거

ORD 기록
ord-09ee8fe9a13c4dd7afeec0bb2349df8b
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06288073B1

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