Hydrochloric Acid → 4-[2-(4-Aminophenyl)ethoxy]benzaldehyde

HRID 1595497

반응식

HRID 1595497 반응식
[CH:1]([C:3]1[CH:25]=[CH:24][C:6]([O:7][CH2:8][CH2:9][C:10]2[CH:15]=[CH:14][C:13]([NH:16]C(=O)OC(C)(C)C)=[CH:12][CH:11]=2)=[CH:5][CH:4]=1)=[O:2].Cl>C(OCC)(=O)C>[NH2:16][C:13]1[CH:14]=[CH:15][C:10]([CH2:9][CH2:8][O:7][C:6]2[CH:5]=[CH:4][C:3]([CH:1]=[O:2])=[CH:25][CH:24]=2)=[CH:11][CH:12]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 21704970tert-butyl N-{4-[2-(4-formylphenoxy)ethyl]phenyl}carbamate

생성물 1

HCID 217050034-[2-(4-Aminophenyl)ethoxy]benzaldehyde수율 141.9%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

5 g (14.6 mmole) tert-butyl N-{4-[2-(4-formylphenoxy)ethyl]phenyl}carbamate was deprotected in ethyl acetate saturated with hydrochloric acid at room temperature over night. The product precipitated and filtration yielded 5 g (100%) of 4-[2-(4-aminophenyl)ethoxy]benzaldehyde x HCl. The product contained some solvent, but was used without further purification.

후처리

  1. customThe product precipitated
  2. filtrationfiltration

출처 및 근거

ORD 기록
ord-3852a4ec30f447a98636b3b2dc37171d
출처 데이터셋
uspto-grants-2001_09
특허 번호
US06288096B1

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