Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Phenylacrylamide → N1-Phenyl-3-(7-benzyl-3,7-diazabicyclo[3.3.1]non-3-yl)propanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Phenylacrylamide | HCID 221792 | — |
| 반응물 | 3-Benzyl-3,7-diazabicyclo[3.3.1]nonane | HCID 13059482 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N1-Phenyl-3-(7-benzyl-3,7-diazabicyclo[3.3.1]non-3-yl)propanamide | HCID 21701928 | 97% |
반응 단계
N1-Phenylacrylamide (1.0 g; 6.8 mmol; from step (a) above) was added to a stirred solution of 3-benzyl-3,7-diazabicyclo[3.3.1]nonane (1.5 g; 6.8 mmol; see Example E above) in EtOH (7 mL). The reaction mixture was stirred for 10 h and concentrated to give the sub-title compound in a 97% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06291475B1 |
| 출처 데이터셋 | uspto-grants-2001_09 |
| ORD ID | ord-f0574f3b183b4cd1bb0361e693c30f5d |
| 출처 메모 | uspto-grants-2001_09 |